Vetri-Bladder Canine is a combination of phytoestrogens that work together to support bladder function and is recommended for spayed females and senior pets to help maintain bladder control. Vetri-Bladder Canine supports healthy bladder function in spayed dogs, normal continence in early spayed dogs and bladder muscle strength. This product contains soy protein extract, which is a source of isoflavones. Isoflavones are phytoestrogens (plant based hormones) that help maintain normal bladder muscle tone lost after spaying or during the aging process. Red Clover Flower Powder is considered to be one of the richest sources of isoflavones (water-soluble chemicals that act like estrogens and are found in many plants) available. The estrogen-like effect of red clover isoflavones may attach to estrogen receptors throughout the body. Specifically, they may attach to those receptors in the bladder that will support normal urinary control.